To further optimize the quality of the blade surface model, a fairing modeling method of blade surface based on a genetic algorithm is proposed. According to the NURBS curve and surface modeling principle, the fairing criterion of minimum strain energy and curvature change rate is established. Then the spline interpolation value points are optimized by the genetic algorithm and compared with the B-spline curve. The value points are modeled by NX. The blade surface is smooth, the curve curvature changes evenly, the strain energy is small, and there are no singular points and redundant inflection points.