The East African Community (EAC) Partner States have a shared vision and have agreed in principle to develop a regional strategy to market and promote the region as “a single tourist destination.” The EAC tourism destination has a comparative advantage of inherited natural resources, core resources and attractors ranging from game parks; cultural and historical sites; mountains; coastal zones and waterfalls; game viewing and gorilla tracking. E-Tourism plays a critical role for the competiveness of tourism organizations and destinations and for the entire tourism industry as a whole. However, application of e-tourism that would enable global visibility of the EAC destination is yet to be fully utilized. There is minimal online information about the EAC tourist destinations and attractions, and online booking is still a challenge. The chapter discusses the global and EAC trends in tourism, the tourist destinations and attractions in East Africa. E-tourism application and its catalystic role in promoting and enhancing the competitiveness of the EAC as a single tourist destination is examined and analysed and challenges and prospects of adopting e-tourism discussed. E-tourism strategic and operational recommendations for promoting EAC as a single competitive tourist destination are put forward.