The effects of decimeter microwaves (irradiation 460 MHz with output power 60 MW, duration 20 min) on functions of the visual system structures: retina, visual cortex and colliculus superior – under the conditions of formation of the focus of increased excitability in the amygdala and hypothalamus were studied. Transformation of patterns of responses in the retina, visual cortex and colliculus superior, being expressed in the most prominent way in the retina, evoked by photostimulus presentation, was shown. The clinical observations (duration: 30 days) revealed aggravation of general status. Immediately after irradiation exposure all studied rabbits showed transient signs of the first stage of kindling by the R. Racine scale; very often seizure jerking movements of limbs was observed. Besides, interictal spikes were registered electrographically.