In an earlier study we had noted that the term transdisciplinary is used in describing a number of different situations, but always implied some form of knowledge-sharing collaboration. Researchers have observed that the requisite knowledge lies both within a development team and outside of it, but how it all works in harmony may vary from case to case. In this paper we explore the utility of a system architecture description standard, ISO 42010 as a framework for representing architectiral knowledge in a consistent way. This is illustrated in a social innovation case study. The case also illustrates how knowledge from social, medical and physical sciences was combined at multiple levels within a telemedicine delivery system.