Using high throughput method of 3D printing, 20 Inconel 718 alloy samples with different Nb contents (0∼10 wt.%) are conveniently prepared in a single printing process, and then analyzed the microscopic morphology and hardness of these samples. The results show that with the increase of Nb content in the alloy, the content of Laves phase in the alloy gradually increases, and the Laves phase particles also become larger, resulting in a gradual increase in hardness. In conclusion, the new technology breaks disadvantages of traditional new material development such as high cost, long time consuming, single trial and error, and provides the possibility for rapid and accurate development of new materials.