Aiming at the hoisting construction technology of precast slab components in an assembled composite underground station, the stress and deformation analysis of precast slab under unbalanced hoisting condition is carried out by establishing a three-dimensional nonlinear finite element simulation model. The results show that the unbalanced hoisting mainly affects the stress of the prefabricated plate member, and the small fluctuation of the deformation will not affect the overall quality of the member. The maximum tensile stress value of prefabricated components exceeds the standard value of concrete tensile strength when lifting 1cm unbalanced hoisting. Unbalanced hoisting will significantly increase the cracking possibility of concrete prefabricated components. In view of the above problems, the lifting construction technology is further proposed, and the 360° rotating universal spreader is specifically developed to improve the efficiency and safety of the prefabricated beam plate lifting. It provides theoretical basis and reference for the hoisting and construction of prefabricated panel member in prefabricated subway stations.