The care of osteoporosis is being revolutionized by developments in AI-enabled exoskeletal robotics, which can improve mobility and facilitate the recovery from fragility fractures. The literature on current advancements in exoskeletal robotics and their therapeutic implications for patients with osteoporosis with particular attention paid to investigations on bone regeneration, functional rehabilitation, and gait analysis, is reviewed in this study, The review focuses on exoskeletons used for mobility aid and polymer-coated synthetic bone grafts, highlighting these technologies’ safety, viability, and efficacy.