An increasing number of countries has been introducing nationwide Electronic Health Records (EHRs) with the aim of improving healthcare processes and enhancing accessibility for patients and caregivers. To ensure these systems effectively meet users’ needs, the continuous process of designing and developing EHRs has to be based on a user-centered approach, focusing on the everyday tasks and challenges of users while interacting with the medical system. This study specifically examines the needs of intra-familial, informal caregivers in the context of nationwide EHRs. Based on an online survey with 608 potential users of EHRs for intrafamilial care, the essential key features have been identified, analyzed, and prioritized. The findings highlight the significance of functionalities supporting caregivers in daily tasks. This research delivers initial insights on aspects regarding potentials and barriers of EHRs for informal care in a familial context.