The research focuses on the protection of infrastructures against the threats posed by Improvised Explosive Devices (IEDs), specifically Vehicle Borne Improvised Explosive Devices (VBIEDs). The primary aim is to develop and test mitigation solutions to enhance the blast resistance of reinforced concrete blast walls (T-walls) and other critical infrastructure components. Used numerical modeling to simulate the behavior of protective coatings and EADs under blast conditions. Developed prototypes of EAD solutions, such as lateral compression tubes and invertubes, and tested them under controlled conditions to evaluate their performance. Elastomeric coatings significantly increased the flexural strength of perforated brick walls, resulting in improved resistance to blast impacts. Static and dynamic tests demonstrated substantial improvements, with experimental data showing credible enhancement under explosion conditions. The advanced protective coatings developed through the PRINSE-APC project effectively reduced the projection of lethal fragments from façade elements. The research offers practical, cost-effective solutions for improving the safety and resilience of infrastructures against explosive threats. The developed technologies and methodologies can be directly applied to military operations and civilian infrastructure protection. The guidelines and best practices established from this research provide a foundation for future advancements in blast mitigation and infrastructure protection.