As a widely used portable measurement and control instrument in the power system, the accuracy and reliability of temperature calibrators are of great significance for ensuring the stable operation of the power system. However, in the calibration process of temperature calibrators, different connecting methods and the selection of cold junction compensation modes will have a significant impact on the calibration results. Therefore, conducting research on laboratory calibration of temperature calibrators and exploring the impact of different cold end compensation methods on calibration results is of great significance for improving the accuracy of calibration results. This paper aims to compare and analyze the application effects of different cold end compensation methods in the calibration process of temperature calibrators, and explore their specific impact mechanism on the calibration results. Through experimental verification and data analysis of different compensation methods, a calibration method that is conducive to improving the accuracy of calibration results is proposed, providing theoretical support and practical guidance for the precise calibration of temperature calibrators.