Based on marine geophysical data collected during the IT-Navy HIGH NORTH20 and HIGH NORTH21 campaigns, a 3D integrated mapping of a region between 78.5-81°N and 1-12°E, where the Molloy Hole is located (Fram Strait – Arctic Ocean), has been developed. The Molloy Hole is the deepest undersea feature of the Arctic Ocean and plays a structural key role in the ocean geodynamics in terms of new ocean seafloor and gravitational mass movement, sink or barrier to the dynamics of the water masses with confined sedimentary processes in the presence of melting ice, polar and Atlantic water. The ocean surface (water and ice), the water column and the seabed data, thanks to an integrated-multidisciplinary approach and harmonization techniques named ‘imagery box’, has been processed using MATLAB R2021b to obtain a high-resolution 3D model. In particular, the research activities collected water column, bathymetry and acoustic backscatter from multibeam sonar surveys, CTD (Conductivity Temperature Depth) data, and sedimentary samples from box corers. The need for visualization to aid in the comprehensive analysis of all elements of this imaginary box is the main reason behind this research. Consequently, it seeks to integrate in situ and remote sensing measurements to provide an integrated mapping of the study area as a one single product. To achieve this goal, it is essential to optimize the process by standardizing the file formats so that all data can converge into a complete 3D depiction of the elements that compose the ocean: sea surface, water column and seafloor. The unification of distinct geospatial data should be of great help to scientists when analyzing their own ‘imaginary boxes’. This mapping is an integrated data product starting from the raw data to create a unique processing tool, and to produce a complete and comprehensive depiction of the 3D marine environment. This 3D integrated mapping highlights the undersea features as the drivers of the dynamics of the Molloy Hole from the sea surface to the ocean bottom.