One of the major day-to-day problems confronting NHS health workers in the United Kingdom is the one that conflicts with their emotional and mental wellness. This is because of various factors, namely, huge workloads because of higher number of patients, which currently leads to long waiting times, overstretched health facilities, understaffing, stress experienced during the recent COVID-19 pandemic, workplace abuses, bullying, harassments, discrimination, and stigmatization based on race, gender, sexual preferences, and exposure to occupational hazards, amongst others. The aim of this research is to propose a smart health informatics architecture that will be useful in promoting emotional and mental wellness among National Health System (NHS) Workers in the United Kingdom. The aim of this prPoject was achieved through the following objectives: (i) survey of current causes of emotional and mental health challenges and needs to solve the problem, amongst NHS workers in England. (ii) designing of a web-based app to assist healthcare professionals cater for emotional and mental challenges (iii) evaluating the web-based app and (iv) proposing a novel Smart Health Architecture for emotional and Mental Wellness for National Health System (NHS) Workers in England, United Kingdom. The significance of this smart architecture cannot be over emphasized. This newly proposed smart health architecture will assist NHS staff to overcome emotional and mental health challenges, especially during, before and after major global pandemic.