To cultivate outstanding engineering talent capable of both adapting to and spearheading regional economic and social progress, as well as to facilitate the transformation and advancement of local economies and to promote collaboration between universities and regional economies, practical teaching bases should be established. Through the strategic alignment and interactive development of practical teaching bases, it may be possible to deepen the integration between industry and education, as well as the interactions between universities and enterprises. Thus, successful teaching bases leverage the academic strengths of universities and the resources offered by businesses. The approach to industry-education integration revolves around refining the model of collaborative education between universities and enterprises, with a specific focus on refining the talent development process. A case of innovative yarn development design within a spinning study practice teaching base is analyzed in this study to investigate the approach. Within this base, student teams have developed ultra-comfortable yarn, stainless steel fiber/lyocell flame-retardant blended yarn, and stainless steel filament/cotton ply-twisted composite yarn. The case study exemplifies the potential for effective cooperation between universities and enterprises in nurturing talent, leveraging dual-teacher training, providing societal contributions, facilitating employment opportunities, and fostering entrepreneurial initiatives. This collaborative model shows significant potential for comprehensively enhancing the quality of talent cultivation, thereby propelling regional economic and social development.