“Semantic space creation” and “distance-computing” are basic functions to realize semantic computing for environmental phenomena memorization, retrieval, analysis, integration and visualization. We have introduced “SPA-based (Sensing, Processing and Actuation) Multi-dimensional Semantic Computing Method” for realizing a global environmental system, “5-Dimensional World Map System”. This method is important to design new environmental systems with Cyber-Physical Space-integration to detect environmental phenomena occurring in a physical-space (real space). This method maps those phenomena to a multi-dimensional semantic-space, performs semantic computing, and actuates the semantic-computing results to the physical space with visualizations for expressing environmental phenomena, causalities and influences. As an actual system of this method, currently, the 5D World Map System is globally utilized as a Global Environmental Semantic Computing System, in SDG14, United-Nations-ESCAP: (https://sdghelpdesk.unescap.org/toolboxes). This paper presents a semantic computing method, focusing on “Time-series-Analytical Semantic-Space Creation and Semantic Distance Computing on 5D World Map System” for realizing global environmental analysis in time-series. This paper also presents the time-series analysis of actual environmental changes on 5D World Map System. The first analysis is on the depth of earthquakes Earthquake with time-series semantic computing on 5D World Map System, which occurred around the world during the period from Aug. 23rd to Aug. 28th, 2014, and Jan 7th to Jan. 13th, 2023. The second is the experimental analysis of the time-series difference extraction on glacier melting phenomena in Mont Blanc, Alps, during the period from 2013 to 2022, and Puncak Jaya (Jayawijaya Mountains), Papua, during the period from 1991 to 2020 as important environmental changes.