Patient-Generated Health Data (PGHD), such as data provided by wearable devices, hold promise to improve health outcomes. However, to improve clinical decision-making, PGHD should be integrated or linked with Electronic Health Records (EHRs). Typically, PGHD data are collected and stored as Personal Health Records (PHRs), outside EHR systems. To address this challenge, we created a conceptual framework for PGHD/EHR interoperability through the Master Patient Index (MPI) and DH-Convener platform. Then, we identified the corresponding Minimum Clinical Data Set (MCDS) of PGHD to be exchanged with EHR. This generic approach can be used as a blueprint in different countries.