This volume contains the papers accepted for the ICIMTH (International Conference on Informatics, Management, and Technology in Healthcare) for the year 2023. The Scientific Programme Committee presents to the academic and professional community of biomedical and health informatics, the scientific outcomes of the ICIMTH 2023 Conference, held from 1–3 July 2023 in Athens, Greece.

The ICIMTH 2023 Conference is the 21st annual conference in this series of scientific events, which gathers scientists working in the field of biomedical and health informatics from all continents. As last year, because the situation as regards the COVID-19 pandemic has improved and restrictions were lifted, the conference was held as a live event. To encourage all presenters to attend the conference, virtual sessions by means of teleconferencing were not offered.

The field of biomedical and health informatics is studied at this conference from a very broad perspective, with the participants presenting research and application outcomes of informatics from cell to populations, including several technologies such as imaging, sensors, biomedical equipment and management and organisational aspects, including legal and social issues. Essentially, data science, informatics, and technology inspire health professionals and informaticians to improve healthcare for the benefit of patients. As was expected, a significant number of papers were still related to the COVID-19 pandemic, but this year we saw an increased influx of submissions in AI studies and applications in healthcare. We wanted this to be reflected in the theme of the conference and the title of the proceedings.

It should be noted that the proceedings are published as an open access eBook with e-access for ease of use and browsing without the loss of any of the advantages of indexing and citation in the biggest scientific literature databases, such as PubMed/Medline and Scopus, that the series of Studies in Health Technology and Informatics (HTI) of IOS Press provides.

At the end of the deadline we had more than 252 submissions, from which, after review, we accepted 149 as full papers, 13 as short communications, and 14 as poster papers.

The organisers would like to thank Dr. Spyros Zogas and Prof. John Mantas for the design of the cover illustration and of the entire conference series. This year the cover illustration signifies the reflection of AI applications in healthcare, as Hygeia faces her mirror automaton image, indicating the possible dangers to healthcare which exist during this extremely fast digital-transformation era of the healthcare system.

The Editors would like to thank the Members of the Scientific Programme Committee, the Organising Committee, and all Reviewers, who performed a very professional, thorough and objective refereeing of the scientific work to achieve a high-quality publishing achievement for a successful scientific event.

Athens, 26.05.2023

The Editors,

John Mantas, Parisis Gallos, Emmanouil Zoulias, Arie Hasman, Mowafa S. Househ, Martha Charalampidou and Andriana Magdalinou.