When linked to wearable biosensors, Intelligent Environments could play a pivotal role in continuously monitoring and securing people’s well-being. We explored the value of one such biosensor that records Electrodermal Activity (EDA) by assessing its correlation with participants’ simultaneously, continuously, self-reported arousal. EDA’s frequency and amplitude of ‘non-specific’ Skin Conductance Responses in low, mid to high, or high levels of arousal were determined. When participants were in mid/high and high arousal situations, self-reports showed significant correlations (p < .001) with both EDA characteristics. With low arousal, no significant correlations were found. So, in cases of elevated stress, EDA shows the potential of being a reliable signal stress and, hence, also monitor of people’s well-being over time. Follow-up studies should further investigate and validate the utility of EDA monitoring as part of a comprehensive health monitoring strategy and its effectiveness in enhancing well-being.