Usability and user experience are central quality attributes of electronic health record (EHR) systems. Usability evaluation studies typically focus on short-term use and situational usability, although feedback collected during operational use provides input for future information systems development. An abundance of studies report on physicians’ dissatisfaction with the usability of their EHR systems and many show an association between poor usability and physician burnout. However, there is a scarcity of large long-term monitoring studies assessing end users’ experiences with EHRs. We report on the results from four large (n=3,929–4,628) national cross-sectional usability surveys conducted among Finnish physicians in 2010, 2014, 2017, and 2021. The main finding was that the perceptions of physicians working in public health centres had changed for the better but those working in public hospitals reported similar or even more negative experiences in 2021 than in 2010–17; they rated only system responsiveness to inputs as having improved. Based on this finding, systematic research-based monitoring of EHR development from the end users’ perspectives should be continued.