The development of the photovoltaic industry is an important support for the promotion of a low-carbon economy. The rapid expansion of photovoltaic power station has also gradually exposed many operating failures. These operating failures will directly affect the operating life, power generation and revenue of the power station. This paper firstly introduces the common quality problems at each stage of the photovoltaic power station operation failure based on the field investigation of the power station, and analyzes the main reasons for the quality problems. The whole process quality control strategy of the photovoltaic power station is proposed, which provides a reference for the development and quality control of the photovoltaic industry.