Excessively high temperatures will interfere with the operation of the components and damage equipment. The key to fixing this is to generate uniform heat dissipation and maximize heat dissipation. This paper proposed a cold plate with three S-type multistage Tesla valves (ST-MSTV). Thermal performance was first evaluated with flow direction and angle. The effects of channel flow direction and valve spacing on the cold plate were then investigated with Ansys Fluent software. The standard deviation of temperature was helpful in representing the uniformity of the temperature of the cold plate. The heat transfer capability of the three-channel ST-MSTV was proven to be effective on the fact that reverse flow causes fluid mixing and vortices. The flow channel form of scheme 2 is better than other schemes, showing the best temperature uniformity and the most effective cooling performance when the valve spacing is 30 mm.