Diabetes has become one of the most fatal diseases as a result of lifestyle changes, food habits, and decreased physical exercise. Diabetes is believed to afflict 422 million people globally, according to the latest WHO estimates. Having said that, the Type II category of diabetes is more fatal because it is determined by the body’s insulin resistance. Furthermore, Type II diabetes has been linked to complications with the kidneys, eyes, and heart. A big number of scientists are also looking into the possibility of a link between diabetes and cancer. We present an overview of such discoveries as well as our cancer research efforts in this report. Dimensionality reduction, Classification, and Clustering are applied in the proposed work to compare with the existing classifiers. PIMA Indian diabetes datasets and Stanford AIM-94 dataset is considered as the benchmark dataset for performing experimentation.