In order to explore the effect of different textures on human emotions under different sensory conditions, we collected the effective tendency of textures of six types from 18 to 30 years old subjects in visual, tactile and auditory experiments through psycho-physical experiment. The results show that the subjects have different emotional feelings for textures under different senses. But in all experiments, wood is a relatively safe and reliable textures in subjects’ cognition. This essay, through the study of textures, aims to raise design suggestions on the use of large medical equipment.