The Yigong landslide is simulated and analyzed with a combined finite-discrete method (FDEM) under seismic loading. Determination of computing model and parameters are introduced. The final distances of six reference points are given showing a special distribution in accord with the results of field investigation. Also, the velocity time-history curves of these points are depicted, where two trends are captured for these points matching with the sliding process of the Yigong landslide. Inconsistencies of displacements and velocities of these points result from the generation and propagation of cracks, initiating the landslide eventually. The FDEM works well in the simulation of this landslide, revealing its applicability and advantages.