Alzheimer’s disease (AD) has become a major issue around world, including China. The two major challenges for AD are the difficulty in early detection and poor treatment outcomes. Over the past decades, artificial intelligence (AI) was more and more widely used in the prevention, diagnosis and treatment of AD, which might be helpful to deal with the aging of population in China. Here, after a systematic literature searching on three English databases (MEDLINE, EMBASE, the Cochrane library), we briefly reviewed recent progress on the utilization of AI in the susceptibility analysis, diagnosis and management of AD. However, it is still in its infancy. More researches should be performed to improve the prognosis of patients with AD in the future.