Recent developments of Artificial Intelligence, Machine Learning and Big Data technologies are posing a threat to white-collar workers and managers alike. Whereas until a few years ago only manual jobs were at risk of replacement, nowadays there is no guarantee that intellectual jobs will remain in human’s hands for long. Hopes that new technologies will generate more new jobs than those lost are vanishing. The new challenge faced by human workers is made up of entities that display more intelligence, whether real or just simulated, than them. We, as humans, need to invent new strategies to survive in a job market that seems ready, in one or two generations, to get rid of us. This paper identifies the main issues around intelligence and provides hints about what intelligence imitation/simulation cannot do that human intelligence can. It also discusses aspects of creativity, allegedly a human-only skill that looks like the most promising area in which human development may progress, reducing risk of silicon replacement.