In this paper, we scrutinize the effectiveness of various clustering techniques, investigating their applicability in Cultural Heritage monitoring applications. In the context of this paper, we detect the level of decomposition and corrosion on the walls of Saint Nicholas fort in Rhodes utilizing hyperspectral images. A total of 6 different clustering approaches have been evaluated over a set of 14 different orthorectified hyperspectral images. Experimental setup in this study involves K-means, Spectral, Meanshift, DBSCAN, Birch and Optics algorithms. For each of these techniques we evaluate its performance by the use of performance metrics such as Calinski-Harabasz, Davies-Bouldin indexes and Silhouette value. In this approach, we evaluate the outcomes of the clustering methods by comparing them with a set of annotated images which denotes the ground truth regarding the decomposition and/or corrosion area of the original images. The results depict that a few clustering techniques applied on the given dataset succeeded decent accuracy, precision, recall and f1 scores. Eventually, it was observed that the deterioration was detected quite accurately.