Social protection systems are in a major process of transformation. Solutions from the past are no longer valid, or at least valid without important adaptations, to address future adequacy, sustainability, and quality of social protections systems. Ageing, changes in the world of work and in the evolving aspirations of citizens will impact, even more than today, on the features of the welfare of the future. Supporting a social investment approach in the agenda of modernization to be pursued, which recognize the relevant role to be played by social innovation, will be a key aspect of the reforms that are needed. ICTs would help in ensuring cost effective services, reducing fragmentation, and favouring integrated social services. This will be, no doubt, a multi-faceted and complex process, but there are choices that can make a difference in maximizing the potential that ICT, s can bring: An adequate leading role of public authorities and institutions at different territorial levels; a full involvement of all relevant stakeholders in a framework of reinforced and changing relationships; and a strategic outcome-based approach, supported by evidence-outcomes will contribute to unleash this potential. This article analyses, based on relevant successful experiences, some of the major interactions involved in the development and translation of enabling-ICTs to the fulfilment of social policy objectives.