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Building an I2B2-Based Population Repository for Clinical Research
Lydia González, David Pérez-Rey, Enrique Alonso, Gema Hernández, Pablo Serrano, Miguel Pedrera, Agustín Gómez, Kristof De Schepper, Titus Crepain, Brecht Claerhout
The present work provides a real-world case of the connection process of a hospital, 12 de Octubre University Hospital in Spain, to the TriNetX research network, transforming a compilation of disparate sources into a single harmonized repository which is automatically refreshed every day. It describes the different integration phases: terminology core datasets, specialized sources and eventually automatic refreshment. It also explains the work performed on semantic normalization of the involved clinical terminologies; as well as the resulting benefits the InSite platform services have enabled in the form of research opportunities for the hospital.
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