The challenge of developing and nurturing research-practice synergy and integration in emergency management and disaster risk reduction is typically described as a challenging multidimensional vision. This paper describes and critically analyses the continuous and comprehensive Israeli effort since 2016 to promote this vision. It relates to the cultural, social, organizational, strategic policy and other aspects of this process. The new applied research-practice emerging and synergetic ecosystem is described and analyzed. Strategically speaking, applied and scientific, local and international implications are discussed.