In order to meet various passengers' travel demand, improve passenger service levels and get the optimal running plan foe fast and slow trains, which make the minimum travel time of all passengers, this paper establishes an optimal fast and slow train stop model with passengers' transfer behavior and solves the model and analyzes the data with MATLAB. Under the premise of this article, compared with the traditional plan with the same departure frequency, the optimal plan can save travel time of 10980 minutes, that is, 15.3 s/per. After analyzing the proportion of passengers with different riding distances, it is concluded in this paper, the optimal proportion of passengers is, short distance: middle distance: long distance=20.9%:32.8%:46.4%, and the saving time is 29.3s/per.