Objective: Daily assessment of the acid-base balance (ABB) in blood is one of the important elements of multi-parameter patient monitoring at intensive care units (ICUs). The present work aims to determine the effectiveness and validity of the integral homeostasis index IHx calculated from ABB blood test data for the assessment and prognosis of children with critical traumatic conditions.

Methods: 345 patients were studied. IHx was calculated and the data were subjected to statistical evaluation. An Arden-Syntax-based clinical decision support (CDS) platform was used. One purpose of the study was to incorporate the platform into the ICU IT landscape of the hospital, and the second purpose was to develop a CDS module for the calculation of IHx and present the results in real time to the attending physician.

Results: Integral homeostasis index IHx calculations as well as their prompt assessment permit better and more rapid treatment of children with severe traumatic injury.