A range of telehealth applications have been developed. In Canada, telehealth shows considerable promise given the country's large geographical area and need for support in rural areas. In this paper, the authors describe our method for ensuring the quality and safety of telehealth applications by applying clinical simulations. These simulations allow for testing and fine-tuning of telehealth applications before they are released on a large scale. Two applications are briefly described, one involving tele-triage and a second involving tele-nursing. The potential of the approach is discussed along with considerations in its application to ensure the quality and safety of telehealth technologies.