Industry 4.0 is the name for the latest trend in industrial systems for automation of services, cyber physical system and data exchange between multiple players. These system have unique trusted computing cyber requirements. Many time the machine is pitted against a MATE (Man at-the-end) adversary. MATE threats require new requirements on hardware. These requirements are addressed by virtually all major hardware vendors. In this chapter we will discuss the threats, hardware capabilities and use cases offered by major hardware vendors to address Industry 4.0 hardware requirements.