Graphene and halloysite nano-clay have been employed as reinforcements in polymeric nanocomposites due to their superior properties such as high strength, thermal conductivity while epoxy and polyester (PE) are the most popular polymers that have been widely applied in industry as structural material. In the present study, GNP and halloysite nano-clay were used as nano-fillers to reinforce epoxy and polyester matrix, respectively. Micro end milling trials were conducted on a 3-axis ultraprecision CNC machine tool and cutting forces were measured. Higher cutting forces were recorded when cutting graphene/epoxy specimens compared with the nano-clay/PE at higher cutting speed of 188.5 m/min.