Cloud computing is a reality in most business sectors. Hospitals have been more reluctant to adopt cloud technology due to strict data security regulations. Cloud could provide economies of scale reducing Information Technology spending in the Greek state-owned hospitals, while giving the opportunity to the hospitals to upgrade their profile offering web-based services. We propose a simple, robust and easy to apply approach for the Greek hospitals, focusing on clinical and laboratory data in order to move to the cloud environment. To the best of our knowledge, there is no other study regarding the adoption of cloud infrastructure in the Greek hospital sector. This innovative method could transform the business model of the hospitals.