Taiwan has been confronted with a serious problem of aging in recent years. The prevalence of the chronic diseases caused by aging is increased continuously, which has led to a high percentage of comorbidity and polypharmacy. The proportion of the elderly people with polypharmacy (over three to five kinds of drugs) is 81%. Under the situation of high comorbidity, the potentially inappropriate drug for the elderly have become a series problem. However, in order to promote personal health management, Taiwan's Ministry of Health and Welfare has released a service of “My Health Bank”, which contains all the personal medical information issued by the National Health Insurance Department and can be downloaded by any individual person. This study designs a cloud-based personal health management platform to parse and store the information of “My Health Bank”, establishes two databases, one for the health insurance drug table and one for the inappropriate medications. A warning of inappropriate personal medication will be generated based on a checking process. We expect that the application will enhance the safety of medication and improve the self-health management of the elderly.