Healthcare is currently being transformed by the introduction of genomic sequencing – a major advancement in personalised medicine. This advent provides new opportunities for clinicians to use genomic data in decision making about patient diagnosis and treatment, but this can only be achieved through access to data and support in its use. Engaging with clinicians in the development of decision support tools will optimise relevance and adoption of genomic sequencing in healthcare. In this study, existing data from clinician workshops and interviews together with horizon scanning of relevant technologies were used to define clinician portal specifications. We describe a preliminary structure of a decision support tool for use by clinicians and the manner in which the technology may be evaluated.