While some technological breakthroughs enable the development of increasingly destructive weapons, others will provide security agencies with new pre-detection tools. In preamble to a NATO Advanced Research Workshop on the potential role of new technologies and methods to pre-detect potential terrorism intent, an expert RTD was conducted on this subject. It assessed the potential effectiveness, likelihood, and easiness of implementation of some 19 new technologies and detection methods as well as their eventual unintended consequences. This chapter presents the results and analysis of that assessment.