NATO Euro-Atlantic Disaster Response Coordination Center's consequence management field exercise (FX) Ukraine 2015 was co-sponsored by Ukraine and its State Emergency Service. Over 29 nations committed resources, equipment, exercise participants, directing staff and/or observers. Planning was compressed, with 2 formal planning conferences and an in-progress review in less than 4-month to plan an event that consisted of 2 days of academics, a 2-day command post exercise (CPX), a day-long 18-hour FX and a capabilities demonstration day for invited dignitaries. The lead-in scenario used seismic activity resulting from an underground sulfur mine accident to generate broad-spectrum emergency management response requirements: Urban Search and Rescue, restoration of public services, toxic industrial chemical releases, decontamination, environmental impact surveys, medical triage/treatments and a recovered radiation source. The Multinational Telemedicine System (MnTS), which is being developed under the NATO Science for Peace and Security Program, was successfully tested during a field exercise in Lviv, Ukraine in September 2015, attended by NATO Secretary General Jens Stoltenberg and the President of Ukraine, Petro Poroshenko. The exercise permitted the first time use of the MnTS, an independent multinational telemedicine system, to enable provision of medical support in a disaster situation. While telemedicine/telehealth services do not replace real medical personnel, they do augment the teams on the ground with expertise that is not present at the scene of the disaster. Often case the medical infrastructure gets damaged, destroyed or otherwise compromise during disasters. This chapter describes how the multinational telemedicine system was used in simulated disaster conditions.