Telemedicine describes the exchange of medical information between different sites using telecommunications and information systems. Telemedicine helps to improve health status and medical care for those who live in remote areas and who do not have easy access to medical services. In the event of a disaster, telemedicine can enable physicians located in different parts of the world to provide healthcare services remotely, to those found in disaster zones. Disaster management makes use of multiple technologies to provide services in the disaster zones. The idea of using telemedicine in disasters has been around for more than four decades. During the last several decades, there have been many initiatives from the military, space programs, and various governmental agencies to test and evaluate modern telemedicine applications in real and simulated civilian disaster scenarios. The aim of this chapter is to discuss telemedicine applications and how there can be integrated into disaster scenarios, and more specifically, the application and use of technology in the Multinational Telemedicine System (MnTS).