E-Commerce is a business mode based on internet and information technology. Data mining techniques are widely used in E-Commerce for digging out patterns and retrieving information from large scale noisy datasets. The booming of E-Commerce enables businesses to collect large amount of data which could be analyzed for enhancing revenues. The abundant data collected online is the foundation of big data analysis. How to employ data mining models on strategizing and making business decisions is an important topic in recent years. This paper talks about data mining and its application in E-Commerce. The application of data mining in electronic commerce developed based on data mining technology of electronic commerce system to strengthen the ability of business information analysis, it is concluded that the intrinsic relationship between data and extract the useful information, to provide the expected information of the electronic commerce for the business management personnel, to ensure the effective operation of the electronic commerce. Data mining techniques could be used for automated data analysis, pattern identification, information retrieving, business strategizing as well as providing personalized services.