Cardiovascular disease (CVD) has emerged as the dominant chronic disease in many parts of the word. At the beginning of the 21^st century, CVD account for nearly half of all deaths in the developed world and about twenty five percent in the developing word. Cardiological Service in Republic of Moldova is a structure relatively young and it is in permanent reshape. There are no national data on the real number of cardiac patients. Epidemiological studies of terrain (1998–2002) have shown that there are enormous differences of usage of new technologies in different regions. We have big problems with insufficient financing of health and public cardiological service. The future national Program of prevention and treatment of CVD will have the aim to contribute to find out all of cardiac patients and distinguish the groups of high risk from the healthy population. Based on the epidemiological situation we need to elaboration some national project, including as e-health, Telemedicine/Telecardiology for implementation in our health system.