The crisis in Ukraine has influenced the way in which the security options of the Republic of Moldova are analyzed. On the other hand, this phenomenon determined an increased interest from the European structures towards the Republic of Moldova. These two aspects of the crisis from Ukraine reflect the uncertainty persisting in the Moldovan society related to the security of the territory under the State border. It should be mentioned that the crisis in Ukraine determined a retreatment reaction on behalf of the Government of the Republic of Moldova, which came back to a reactive and defensive behavior in relation to Russia. At the same time, such a reaction led to the resuscitation of some pro-NATO attitudes expressed during the election campaign (autumn 2014) by the liberal parties. This behavior also reflects an old cleavage from the Republic of Moldova – the neutrality adepts versus those who support the joining of the country to the North-Atlantic Alliance. In this context, this article will assess the main trends in the security system of the Republic of Moldova from the perspective of the Ukrainian crisis consequences. And finally, we cannot neglect the fact that the Republic of Moldova – a state with profound vulnerabilities in the area of security and defense – should be concerned more than ever with the assessment of the alternatives existing for ensuring its own security. Unfortunately, the political instability, but mainly the lack of will, courage, and vision among the ruling parties, has determined the lack of any progress in the area related to enhancing the capacities of the country in the area of security and defense.