Maternal Mortality Ratio (MMR) in many African countries has consistently been in the range of 500–800 per 100,000 live births over the last two decades. A major challenge in these settings relates to the quality and promptness of antenatal and/or post-natal care given. Recent advancements in technology, notably health information systems (HIS), have helped in the response to many of these challenges. In Africa, and indeed Nigeria, there is yet a comprehensive HIS that cuts across health sector that can address these issues. Hence, this project seeks to design a Secured Cloud-Based Antenatal and Postnatal Clinic System of a Health Information System to assist in efficient utilization of material and human resources and enhance quality of delivery of health services, geared towards improving maternal health. Requirements gathering for the proposed system will be conducted through a study of Antenatal and Postnatal Clinic Systems of existing Cloud Based HIS. System Modeling and Implementation Evaluation would be carried out. The developed HIS will adopt a AGATE architecture (Stakes and objectives of the system Description of the related organizations, processes and information flows, Security requirements, Services of the system, and traceability with operational needs), and a test-run and evaluation of the completed project will be conducted at specified three primary health care facilities in Nigeria.