The purpose of this study is to theoretically develop and empirically examine a general coping theory model which explicates the indirect effects of key job-related techno-stressors on job exhaustion. Through this study, we show that techno-stress creators are detrimental to employee well-being and should be treated accordingly. Specifically, we first argue that key techno-stress creators on the job, namely techno-invasion and techno-overload, drive unpleasant states such as work-family conflict and distress. Next, we rely on general coping theory and argue that people respond to these states differently, but with both adaptive and maladaptive technology-specific coping strategies. Adaptive coping behaviors are argued to ultimately reduce work exhaustion, and maladaptive coping strategies are argued to increase it. The proposed model was tested and validated with structural equation modeling techniques applied to self-reported data obtained from a sample of 242 employees of a large organization in the United States. Implications for theory and practice are discussed.