The aim of this chapter is to introduce and discuss the potential socio-technical barriers that might be hindering the adoption of Secure Multiparty Computation (SMC) techniques. By investigating the conditions of adoption of technology under development, we are able to find different solutions that support the technology adoption process. We set out to interview the potential future users of SMC technologies to investigate the most likely adopters and to find the best directions for future developments of SMC. SMC is compared with the existing practices of data handling to demonstrate its advantages as well as disadvantages. In the current development phase, the focus of SMC advances needs to be on the usefulness and on finding an appropriate niche for the technology.