Nuclear Magnetic Resonance is a very powerful technique to study water and aqueous systems. In particular, it is a very local probe with atomistic sensibility. It takes advantage of different probe-heads and numerous pulse sequences to study the structural and dynamical properties of the system. In this work we highlight the application of several of these methodologies for the comprehension of important phenomena such as the dynamical crossover in supercooled water, the clustering dynamics of water/methanol solution and the folding/unfolding process of hydrated lysozyme. Both technical details and physical implications will be discussed.