The second KES International Conference on Innovation in Medicine and Healthcare (InMed-14) was held over 9–11 July 2014 in San Sebastian, Spain, organised by KES International in partnership with the University of the Basque Country, UPV/EHU and the Institute of Knowledge Transfer.

InMed-14 gathered researchers and engineers, managers, students and practitioners from a broad medically-related arena. This multi-disciplinary group met to discuss the ways that technological and methodological innovation, knowledge exchange and enterprise can be applied to issues relating to medicine, surgery, healthcare and the issues of an ageing population. A central theme of the conference was Smart Medical and Healthcare Systems which covered the ways in which modern intelligent systems contribute to the solution of problems faced by healthcare and medical practitioners today, addressing the application of these systems.

The conference featured five excellent keynote talks from internationally renowned experts, namely:

• Edward J. Ciaccio, Columbia University, NY (talk entitled ‘Model of Reentrant Ventricular Tachycardia based on Wavefront Curvature’);

• Jesus Cortes, Biocruces, Ikerbasque, Spain (talk entitled ‘Computational Neuroimaging for Health and Disease’);

• Juan Manuel Gorriz, University of Granada, Spain (talk entitled ‘DiagnoSIS: Diagnosis by means of Statistical and Intelligent Systems’);

• Ricardo Sanchez Peña, ITBA & CONICET, Argentina (talk entitled ‘Automatic Control of Diabetes type 1’); and

• Sebastiano Stramaglia, Ikerbasque Visiting Professor, Spain (talk entitled ‘Causality measures for Brain Computation’).

In addition to the General Track, chaired by Prof Manuel Grana, University of the Basque Country UPV/EHU and the Workshop on Smart Medical and Healthcare, chaired by Dr Carlos Toro, Vicomtech-IK4, Systems, there were special sessions on Medical Decision-Support Systems chaired by Dr Elena Hernández-Pereira, University of La Coruña, Spain; Computer-aided Image Analyis in Ophthalmology chaired by Prof Manuel Penedo, University of La Coruña, Spain; and Advances in Data & Knowledge Management for Healthcare chaired by Dr Massimo Esposito, National Research Council of Italy (ICAR-CNR).

These proceedings consist of 43 papers that were presented at the conference, each of which was comprehensively reviewed by at least two members of the International Programme Committee.

We hope this will form a useful and interesting reference for further research on this topic.

The InMed-14 Conference Chairs:

Manuel Graña, Robert J. Howlett, Lakhmi C. Jain and Carlos Toro