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Using an Ontological Modeling to Evaluate the Consistency of Clinical Practice Guidelines: Application to the Comparison of Three Guidelines on the Management of Adult Hypertension
Alexandre Galopin, Jacques Bouaud, Suzanne Pereira, Brigitte Séroussi
Every year, numerous clinical practice guidelines (CPGs) are published on a same topic. They may be conflicting, thus infringing clinicians' confidence in adhering to them. In order to build a clinical decision support system to assist GPs in the management of hypertension, we have considered three recent CPGs written in French. We developed a methodological framework to evaluate how consistent the three CPGs were. After a manual extraction of recommendation rules, all patient profiles covered by the CPGs have been identified. Then, ontological modeling and reasoning were used to build a subsumption graph of all profiles. This graph allows the retrieval of recommendations that could be conflicting. Results show that if rules are different in the three CPGs according to a document-based approach, many profiles are related through subsumption, and no critical inconsistencies were discovered when implementing an ontological modeling.
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