Recent advances in serious games and computer game engines' development as well as successful applications of serious games concepts/mechanics/mechanisms in corporate management, administration, business, marketing, training, learning, education, wellness and ecology initiatives, and healthcare stimulated initial “serious games” (or, “gamification”) research, design and development. The goals of this conceptual paper are to a) describe the current status of gamification, b) provide designed and developed examples of successful applications of serious computer game development technologies to produce quality knowledge and skills in computer science, and c) show that a collaborative work of various specialists in computer science – software engineers, advanced programmers, graphic user interface designers, human-computer interaction experts, specialists in computer graphics, networking, security databases, and artificial intelligence – is necessary to produce quality developers (technologists) of serious games and gamification applications for real-world simulations and education (edutainment).